NAIMS Workshop - 2023

The North American Imaging in Multiple Sclerosis Cooperative (NAIMS) Workshop took place Tuesday, February 21, and Wednesday, February 22 at the Marriott Marquis San Diego Marina in San Diego, California. The workshop was held ahead of the ACTRIMS Forum 2023, being held February 23-25, 2023 at the Marriot San Diego Marina in San Diego.

The purpose of this workshop was to provide an overview of the state-of-the-art and future perspectives of ultra-high-field (UHF) MRI in multiple sclerosis (MS). This workshop particularly focused on the contributions of 7-tesla (7T) imaging to our understanding of MS pathology and lesion development. Safety considerations and current technical challenges were also discussed with the goal to facilitate the integration of 7T imaging in the clinical workflow. The workshop is targeted toward neurologists and radiologists interested in UHF MRI for clinical research/clinical practice, as well as MRI physicists and image processing scientists interested in developing novel techniques applicable to 7T imaging.

Course Details

Welcome00:08:00
Welcome 00:08:00
Ultra-High Field MRI-Histology Correlations01:06:00
Human Post-Mortem Ultra-High Field-Imaging Histology Correlations 00:33:00
Pre-Clinical Ultra-High Field Imaging-Histology Correlations 00:33:00
Pathogenesis of MS Informed by 7T Imaging02:01:00
Central Vein Sign 00:33:00
Paramagnetic Rim Lesions 00:29:00
Cortical Lesions 00:30:00
Detection of Damage in Normal Appearing Tissue 00:29:00
7T Opportunities & Technical Obstacles03:03:00
Metabolic Imaging (CEST, MRS) 00:28:00
Magnetic Properties Mapping (T2*, T1, MTR, Frequency, QSM, etc) 00:30:00
Sodium Quantification Using MRI 00:30:00
MRI of Brain Myelin (and Iron) 00:34:00
The Spinal Cord 00:30:00
Diffusion MRI at Ultra-High Field in MS 00:31:00
Data Blitz 100:31:00
Cervical Spinal Cord Susceptibility Weighted MRI at 7T: Application to Multiple Sclerosis 00:09:00
Changes in Gyrification in Multiple Sclerosis are Related to Cortical Lesion Load and Worsening Disability 00:11:00
A Pilot Trial of Ocrelizumab for Modulation of Meningeal Enhancement in Multiple Sclerosis 00:11:00
Technical Challenges: Safety, Artifacts, and Reproductibility01:05:00
7T MRI Safety, Artifacts, and Mitigation Strategies 00:33:00
Multi-Center 7T Studies in MS 00:32:00
Data Blitz 200:36:00
Analysis of Meningeal Contrast Enhancement Volume on 7T MRI in Multiple Sclerosis 00:12:00
In Vivo MRI to Detect Potential Remyelination in a Nonhuman Primate Model of Multiple Sclerosis 00:12:00
7T MRI Leptomeningeal Enhancement Longitudinal Dynamics and Association with Cognitive Function in Multiple Sclerosis: A 1-year Study 00:12:00
Integration of 7T Imaging in Clinical Workflow01:03:00
The North American Experience 00:32:00
The European Experience 00:31:00
Data Blitz 300:37:00
Performance Evaluation of Ensemble Algorithms Coupled with 7T MRI and Clinical Features for Predicting Multiple Sclerosis Progression 00:15:00
Using Phase Patterns to Differentiate Lesion Severity in Multiple Sclerosis 00:10:00
Diffusion MRI Biomarkers for Inflammation in Spinal Cord 00:12:00
Elements of a 7T MS Protocol: Technical Discussion02:19:00
Clinical Translation and Technical Discussion 02:19:00
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